YMC CHIRAL PREP CD ST/PM

YMC CHIRAL PREP CD ST/PM

◈ Product Information
YMC CHIRAL PREP CD ST/PM are suitable packing materials for preparative isolation of optical isomers. ST is suitable for use mainly in reversed-phase mode, while PM can be used in both normal-phase and reversed-phase modes. The cost is considerably less than that of the conventional packing materials for optical isomers, and therefore YMC CHIRAL PREP CD ST/PM are appropriate not only for semi-preparative isolation but also for industrial isolation. They are also applicable to simulated moving bed(SMB) chromatography and axial compression columns.

► Point
　• β-cyclodextrin modified silica gel packing material
　• Can separate various optical isomers
　• Can be used in both normal-phase and reversed-phase modes
　• Applicable to large-scale isolation by simulated moving bed(SMB) chromatography
　• Various particle sizes are available
　• Bulk supply at kilogram scale is available
　• Excellent cost performance

► Specification
　- Particle size :10㎛, 20㎛, 50㎛
　- Pore size :120A
　- Usable pH range :2.0-7.0

For preparative isolation of optical isomers

Column :YMC CHIRAL PREP CD ST(10µm, 120Å)
　
Scale up from analytical to preparative conditions is fast and easy with high sample loading.

High isolation performance

Column :YMC CHIRAL PREP CD ST(10µm, 120Å)
　
Scale up from analytical to preparative conditions is fast and easy with high sample loading.

Optical isomer	Column	Load*	Optical purity (F1)	Recovery amount(F1)	Recovery rate(F1)
1.	PM	100mg	>99.9%	49.6mg	99.2%
2.	ST	100mg	>99.9%	47.7mg	94.8%
3.	ST	100mg	>99.9%	38.5mg	77.0%
4.	PM	200mg	>99.9%	96.5mg	96.5%
4.	PM	250mg	>99.9%	114.2mg	91.3%

*Column size :250X20mm I.D.　(10µm, 120Å)
　
Highly pure optical isomers can be obtained with high recovery.

Can be used in both normal-phase and reversed-phase modes

• Column :YMC CHIRAL PREP CD PM(10µm,120Å) 250X4.6 mm I.D.
• Eluent :hexane/ethanol(95/5)
• Flow rate :0.5mL/min
• Temperature :ambient
• Detection :UV at 254 nm
• Injection :5µL(1mg/mL)

 

 

 

 

• Column :YMC CHIRAL PREP CD ST (10µm,120Å) 250X4.6 mm I.D.
• Eluent :20mM KH2PO4(pH4.6) /acetonitrile(99/1)
• Flow rate :1.0mL/min
• Temperature :ambient
• Detection :UV at 220 nm
• Injection :5µL(1mg/mL)

 

 

Besides water, alcohol or acetonitrile, hexane or tetrahydrofuran can be used as mobile phase.

◈ Ordering Information

YMC CHIRAL PREP CD ST/PM Analytical Columns
Packing material	Particle size (µm)	Pore size (Å)	Column size Inner diameter x length(mm)	Product Number
ST	S-10	120	4.6 X 250	ST12S11-2546WT
PM			4.6 X 250	PM12S11-2546WT
YMC CHIRAL PREP CD ST/PM Packing material
Product name		Particle size (µm)	Pore size(Å)	Product Number
YMC CHIRAL PREP CD ST		10	120	ST12S11
		20		ST12S21
		30		ST12S50
YMC CHIRAL PREP CD PM		10		PM12S11
		20		PM12S21
		30		PM12S50